Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359548 | 0.86 | ALDH1A1 (0.71) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL187706 | 0.83 | L3MBTL1 (1.00) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL6423922 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL7170509 | 0.81 | L3MBTL1 (0.70) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL8931070 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL10799049 | 0.81 | L3MBTL1 (0.59) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL28995612 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL9844713 | 0.79 | ALDH1A1 (0.79) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL6366586 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL9393651 | 0.79 | MAPT (0.67) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4794125-A | BIS-ALPHA-HALOACYL-AMINOANTHRAQUINONE; ANTITUMOR, LEUKEMIA TREATMENT | CL PHARMA AG (AT) | 1988-12-27 | — | — | US | disclosed |