SCHEMBL8931082

SCHEMBL8931082

C(=C/c1ccc(-c2nc3ccccc3[nH]2)cc1)\c1ccc(-c2nc3ccccc3[nH]2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 11/20 0.70
▸ RAB9A P51151 11/20 0.70
▸ GAA P10253 2/20 0.70
▸ KDM4E B2RXH2 11/20 0.67
▸ ALDH1A1 P00352 10/20 0.67
▸ SMN1; SMN2 Q16637 8/20 0.67
▸ HPGD P15428 5/20 0.67
▸ MAPT P10636 5/20 0.67
▸ HSD17B10 Q99714 3/20 0.67
▸ TP53 P04637 3/20 0.67
▸ POLB P06746 2/20 0.67
▸ GFER P55789 1/20 0.67
▸ PKN1 Q16512 1/20 0.64
▸ PKN2 Q16513 1/20 0.64
▸ PKM P14618 5/20 0.62
▸ ABCB11 O95342 1/20 0.62
▸ NPSR1 Q6W5P4 1/20 0.62
▸ HDAC6 Q9UBN7 1/20 0.61
▸ KMT2A Q03164 5/20 0.58
▸ MMP2 P08253 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388879 1.00 NPC1 (0.70) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL1193922 0.92 NPC1 (0.71) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL1193924 0.92 NPC1 (0.71) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL29386825 0.89 NPC1 (0.88) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2178266 0.89 NPC1 (0.88) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL24295036 0.87 NPC1 (0.84) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL10609442 0.86 NPC1 (0.66) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL28130892 0.86 NPC1 (0.66) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2617477 0.86 NPC1 (0.66) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL22499602 0.85 NPC1 (0.81) NPC1RAB9AGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237519-B1 POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE ABU DHABI POLYMERS CO LTD BOROUGE LLC (AE) 2019-10-30 — — EP disclosed
US-10301460-B2 Polypropylene with enhanced visual appearance BOREALIS AG (AT) 2019-05-28 — — US disclosed
EP-3394162-A1 PREPARATION PROCESS FOR POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE ABU DHABI POLYMERS CO. LTD (BOROUGE) LLC. (AE) 2018-10-31 — — EP disclosed
US-20170355839-A1 POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE BOREALIS AG (AT) 2017-12-14 — — US disclosed
EP-3237519-A1 POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE Abu Dhabi Polymers Co. Ltd (Borouge) LLC. (AE) 2017-11-01 — — EP disclosed
WO-2017108771-A1 PREPARATION PROCESS FOR POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE ABU DHABI POLYMERS CO. LTD (BOROUGE) L.L.C. (AE) 2017-06-29 — — WO disclosed
EP-3184584-A1 PREPARATION PROCESS FOR POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE Abu Dhabi Polymers Co. Ltd (Borouge) LLC. (AE) 2017-06-28 — — EP disclosed
WO-2016102465-A1 POLYPROPYLENE WITH ENHANCED VISUAL APPEARANCE ABU DHABI POLYMERS CO. LTD (BOROUGE) L.L.C. (AE) 2016-06-30 — — WO disclosed
US-20070249840-A1 Process for the preparation of bis-benzazolyl compounds ELIU VICTOR P 2007-10-25 — — US disclosed
US-20070249840-A1 Process for the preparation of bis-benzazolyl compounds ELIU VICTOR P 2007-10-25 — — US disclosed
EP-0086614-B2 Liquid detergent compositions ALBRIGHT & WILSON (GB) 1997-11-19 — — EP disclosed
EP-0086614-B1 LIQUID DETERGENT COMPOSITIONS Albright & Wilson Limited (GB) 1989-10-18 — — EP disclosed
EP-0028038-B1 ISOTROPIC LIQUID DETERGENT COMPOSITIONS CONTAINING MULTICOMPONENT ACTIVE SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1984-07-25 — — EP disclosed
EP-0028038-A1 Isotropic liquid detergent compositions containing multicomponent active system THE PROCTER & GAMBLE COMPANY (US) 1981-05-06 — — EP disclosed
US-4247424-A WATER IN OIL EMULSIONS INCLUDING A HYDROPHOBIC EMULSIFIER, NONIONIC SURFACTANT, AMINE OXIDE, AND A SOAP BUILDER; FOR USE IN COLD WATER THE PROCTER & GAMBLE COMPANY (US) 1981-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249840-A1 Process for the preparation of bis-benzazolyl compounds HBZ, H1-3, HBS1L NPC1 3829/4885RAB9A 2925/4885GAA 4089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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