Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878336 | 0.93 | DGAT1 (0.53) | DGAT1MGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL8931691 | 0.90 | DGAT1 (0.53) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8926249 | 0.89 | DGAT1 (0.51) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8814915 | 0.89 | DGAT1 (0.51) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8927569 | 0.89 | DGAT1 (0.53) | DGAT1LMNAKDM4EAKR1C3ALDH1A1 | |
| SCHEMBL8927053 | 0.89 | DGAT1 (0.48) | DGAT1MGLLLMNAKDM4EALDH1A1 | |
| SCHEMBL8931761 | 0.88 | DGAT1 (0.54) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8814492 | 0.88 | DGAT1 (0.48) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8931682 | 0.88 | DGAT1 (0.48) | DGAT1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8813497 | 0.88 | DGAT1 (0.48) | DGAT1MGLLLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770074-A1 | ANTI-HELICOBACTER ACYL DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-05-02 | — | — | EP | claimed |
| WO-1996001822-A1 | ANTI-HELICOBACTER ACYL DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-01-25 | — | — | WO | claimed |
| US-5637592-A | TREATING HELICOBACTER INFECTIONS, SUCH AS GASTRITIS, STOMACH ULCERS, DUODENAL ULCERS AND GASTRIC CANCER | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-06-10 | — | — | US | disclosed |
| EP-0770074-A1 | ANTI-HELICOBACTER ACYL DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001822-A1 | ANTI-HELICOBACTER ACYL DERIVATIVES OF AZOLONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-01-25 | — | — | WO | disclosed |