Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 12/20 | 0.59 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.59 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.59 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL23774 | 0.90 | PARP1 (0.71) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL28360111 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL29102653 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL27281597 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL11512422 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL689841 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL1906838 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL1087289 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL15328883 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| Terephthalamide SCHEMBL7508927 | 0.87 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753027-A1 | THERMOPLASTIC ELASTOMERS HAVING IMPROVED SURFACE PROPERTIES | ADVANCED ELASTOMER SYSTEMS (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026380-A1 | THERMOPLASTIC ELASTOMERS HAVING IMPROVED SURFACE PROPERTIES | ADVANCED ELASTOMER SYSTEMS, L.P. (US) | 1995-10-05 | — | — | WO | disclosed |
| EP-0436080-A2 | Core-shell polymer and its use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-10 | — | — | EP | disclosed |
| EP-0423628-A2 | Core-shell polymer, resin composition and molded article thereof | Takeda Chemical Industries, Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0258040-A1 | Thermoplastic resin composition comprising a polyamide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-02 | — | — | EP | disclosed |
| EP-0154245-A2 | Process for the fabrication of copolyamides from adipic acid, terephthalic acid and hexamethylene diamine | BAYER AG (DE) | 1985-09-11 | — | — | EP | disclosed |