SCHEMBL29186355

SCHEMBL29186355

CCC[C@H]1CC[C@H](c2ccc(-c3ccccc3)cc2F)CC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 16/20 0.43
DGAT1 O75907 1/20 0.41
FFAR4 Q5NUL3 1/20 0.39
KDM4E B2RXH2 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30767887 1.00 OPRL1 (0.43) OPRL1DGAT1FFAR4KDM4ERAB9A
SCHEMBL8931253 0.90 OPRL1 (0.50) OPRL1DGAT1
SCHEMBL8931254 0.90 OPRL1 (0.50) OPRL1DGAT1
SCHEMBL4650777 0.89 CYP2C9 (0.48) OPRL1DGAT1CYP2C9
SCHEMBL17175201 0.85 CYP2C9 (0.45) OPRL1DGAT1CYP2C9
SCHEMBL17175211 0.85 CYP2C9 (0.45) OPRL1DGAT1CYP2C9
SCHEMBL18458893 0.84 CYP2C9 (0.44) OPRL1DGAT1CYP2C9
SCHEMBL16258047 0.84 CYP2C9 (0.44) OPRL1DGAT1CYP2C9
SCHEMBL17897886 0.84 CYP2C9 (0.44) OPRL1DGAT1CYP2C9
SCHEMBL8380868 0.84 KIF11 (0.45) OPRL1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534600-A Isothiocyano trans-cyclohexyl biphenyl liquid crystal compound, and preparation method and application thereof 武汉轻工大学 2024-02-09 CN disclosed