Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931350 | 0.77 | SMN1; SMN2 (0.34) | AKR1B1 | |
| SCHEMBL981439 | 0.76 | HTR7 (0.30) | HTR7AKR1B1 | |
| SCHEMBL576526 | 0.72 | HTR7 (0.48) | HTR7 | |
| SCHEMBL576941 | 0.70 | HTR7 (0.43) | HTR7AKR1B1 | |
| SCHEMBL576487 | 0.68 | AKR1B1 (0.33) | HTR7AKR1B1 | |
| SCHEMBL980842 | 0.68 | AKR1B1 (0.33) | HTR7AKR1B1 | |
| SCHEMBL979122 | 0.68 | AKR1B1 (0.33) | HTR7AKR1B1 | |
| SCHEMBL17972368 | 0.67 | HTR7 (0.33) | HTR7AKR1B1 | |
| SCHEMBL576123 | 0.67 | TSHR (0.35) | HTR7 | |
| SCHEMBL16186315 | 0.67 | HTR7 (0.33) | HTR7AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648498-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | ASTRA AKTIEBOLAG (SE) | 1997-07-15 | — | — | US | disclosed |
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0619815-B1 | PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| US-4822813-A | 3-(2-Haloalkyl)-1,4-oxathiins and 2-(2-haloalkyl)-1,4-dithiins, and treatment of leukemia and tumors therewith | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1989-04-18 | — | — | US | disclosed |