Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931354 | 0.77 | HTR7 (0.32) | AKR1B1 | |
| SCHEMBL981185 | 0.69 | — | — | |
| SCHEMBL5346800 | 0.67 | — | — | |
| SCHEMBL441723 | 0.66 | — | — | |
| SCHEMBL28476837 | 0.65 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL9099166 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL12616582 | 0.64 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL263371 | 0.64 | ALDH1A1 (0.35) | — | |
| SCHEMBL11100164 | 0.64 | SMN1; SMN2 (0.34) | SMN1; SMN2AKR1B1 | |
| SCHEMBL20079554 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648498-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | ASTRA AKTIEBOLAG (SE) | 1997-07-15 | — | — | US | disclosed |
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0619815-B1 | PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |