Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144554 | 0.83 | HTR1F (0.77) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8931377 | 0.73 | HTR1F (0.56) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7141265 | 0.73 | HTR1F (0.76) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8598857 | 0.72 | HTR1F (0.81) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7143303 | 0.72 | HTR1F (1.00) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| Bromide SCHEMBL7138690 | 0.72 | HTR1F (0.80) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7144771 | 0.71 | HTR1F (0.83) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7138726 | 0.71 | HTR1F (0.98) | HTR1FKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7146335 | 0.70 | HTR1F (0.66) | HTR1FKMT2AMEN1MAPTCTDSP1 | |
| SCHEMBL7141051 | 0.70 | HTR1F (0.71) | HTR1FKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |