Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146335 | 0.88 | HTR1F (0.66) | HTR1FALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL7144554 | 0.83 | HTR1F (0.77) | HTR1FALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8931376 | 0.73 | HTR1F (0.55) | HTR1FALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7141265 | 0.73 | HTR1F (0.76) | HTR1FALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7143303 | 0.72 | HTR1F (1.00) | HTR1FALDH1A1HPGDMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7138726 | 0.72 | HTR1F (0.98) | HTR1FALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL7140234 | 0.71 | HTR1F (0.77) | HTR1FALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7141051 | 0.71 | HTR1F (0.71) | HTR1FALDH1A1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL7140335 | 0.70 | HTR1F (0.76) | HTR1FALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7144771 | 0.70 | HTR1F (0.83) | HTR1FALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |