Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 16/20 | 0.46 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931615 | 0.92 | LTA4H (0.39) | LTA4HADRA1DADRA1AADRA1B | |
| Oxalic Acid SCHEMBL8931577 | 0.85 | ALOX5 (0.40) | LTA4H | |
| SCHEMBL4958489 | 0.81 | LTA4H (0.48) | LTA4H | |
| SCHEMBL3154726 | 0.78 | LTA4H (0.62) | LTA4HMOGAT2MGAT2 | |
| SCHEMBL6106525 | 0.78 | LTA4H (0.62) | LTA4HMOGAT2MGAT2 | |
| SCHEMBL8509274 | 0.76 | LTA4H (0.34) | LTA4HADRA1DADRA1AADRA1B | |
| SCHEMBL17150885 | 0.72 | LTA4H (0.52) | LTA4HMOGAT2MGAT2 | |
| SCHEMBL19392919 | 0.72 | LTA4H (0.52) | LTA4HMOGAT2MGAT2 | |
| SCHEMBL4955102 | 0.72 | LTA4H (0.51) | LTA4H | |
| SCHEMBL17381316 | 0.72 | LTA4H (0.52) | LTA4HMOGAT2MGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808316-A1 | VASOCONSTRICTIVE SUBSTITUTED 2,3-DIHYDRO-1,4-DIOXINOPYRIDINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-26 | — | — | EP | claimed |
| WO-1996024596-A1 | VASOCONSTRICTIVE SUBSTITUTED 2,3-DIHYDRO-1,4-DIOXINOPYRIDINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-15 | — | — | WO | claimed |