Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9698015 | 1.00 | ALDH1A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL11398401 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL10426731 | 0.96 | ALDH1A1 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL999681 | 0.96 | ALDH1A1 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.95 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.95 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL25297651 | 0.91 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790911-A | Amphiphilic poly-trimethylene carbonate and preparation method and application thereof | 临沂大学 | 2020-02-14 | — | — | CN | claimed |
| CN-103265624-A | Method for preparing copaxone | CHENGDU SHENGNUO BIOPHARM CO LTD | 2013-08-28 | — | — | CN | claimed |
| EP-4648799-A1 | LIGAND-DRUG CONJUGATES | Sun Pharma Advanced Research Company Ltd (IN) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024150132-A1 | LIGAND-DRUG CONJUGATES | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2024-07-18 | — | — | WO | disclosed |
| CN-107778354-B | Method for synthesizing abarelix | 成都圣诺生物制药有限公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2020078710-A1 | A METHOD FOR PROVIDING AQUEOUS COMPOSITIONS WITH REDUCED CONTENT OF ORGANIC FLUORINATED COMPOUNDS | SOLVAY SA (BE) | 2020-04-23 | — | — | WO | disclosed |
| EP-3632855-A1 | A METHOD FOR PROVIDING AQUEOUS COMPOSITIONS WITH REDUCED CONTENT OF ORGANIC FLUORINATED COMPOUNDS | SOLVAY SA (BE) | 2020-04-08 | — | — | EP | disclosed |
| CN-110790911-A | Amphiphilic poly-trimethylene carbonate and preparation method and application thereof | 临沂大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-106084015-B | method for synthesizing carbetocin | 成都圣诺生物制药有限公司 | 2020-01-31 | — | — | CN | disclosed |
| CN-105524143-B | A method of synthesis Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-4Aph(Hor)-D-4Aph(Cbm)-Leu-Lys(iPr)-Pro-D-Ala-NH2 | 成都圣诺生物制药有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-104628559-B | Ozone oxidation method used for preparing halogenated acetic acid and esters of halogenated acetic acid | 连云港金康医药科技有限公司 | 2017-04-19 | — | — | CN | disclosed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | disclosed |
| EP-0108645-A2 | Novel ailanthone derivative | SUNTORY LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
| EP-0094804-A1 | Glucosaminyl muramyl peptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |
| US-4385169-A | Reactive alpha amino acid polymer | TEIJIN LIMITED (JP) | 1983-05-24 | — | — | US | disclosed |
| US-4370312-A | HAPTENS, TRACERS, ANTIBODIES AND STARTING MATERIALS FOR INTERFERONS | Dr. Karl Thomae Gesellshaft mit beschrankter Haftung (DE) | 1983-01-25 | — | — | US | disclosed |
| EP-0040506-A2 | Reactive polymer and process for the preparation thereof | TEIJIN LIMITED (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4078049-A | Acetylcholine assay | HOFFMANN-LA ROCHE INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4021387-A | PARASITICIDES, ANAPHYLAXIS, BRONCHIAL ASTHMA | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1977-05-03 | — | — | US | disclosed |