Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931127 | 0.96 | DGAT1 (0.72) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL7886309 | 0.90 | DGAT1 (0.74) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8756456 | 0.87 | DGAT1 (0.81) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL7883247 | 0.86 | DGAT1 (0.71) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL9386404 | 0.85 | DGAT1 (0.70) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL13218553 | 0.83 | DGAT1 (1.00) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8755567 | 0.83 | DGAT1 (0.69) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8756019 | 0.83 | DGAT1 (0.69) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL13218506 | 0.83 | DGAT1 (0.66) | DGAT1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL17249820 | 0.82 | DGAT1 (0.68) | DGAT1LMNAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637592-A | TREATING HELICOBACTER INFECTIONS, SUCH AS GASTRITIS, STOMACH ULCERS, DUODENAL ULCERS AND GASTRIC CANCER | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-06-10 | — | — | US | disclosed |