Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931654 | 0.89 | GPR139 (0.40) | L3MBTL1GPR139IGF1RPOLBMAPT | |
| SCHEMBL9457262 | 0.84 | POLB (0.50) | L3MBTL1POLBMAPTCCR1ADRB2 | |
| Water SCHEMBL9457015 | 0.84 | POLB (0.49) | L3MBTL1POLBMAPTCCR1ADRB2 | |
| SCHEMBL8927401 | 0.76 | POLB (0.45) | POLBMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL11070469 | 0.75 | BRD9 (0.54) | L3MBTL1POLBMAPT | |
| SCHEMBL27443728 | 0.74 | IGF1R (0.37) | IGF1RMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL23565525 | 0.73 | GPR139 (0.48) | GPR139 | |
| SCHEMBL5536931 | 0.72 | KCNA5 (0.53) | L3MBTL1MAPT | |
| SCHEMBL11069372 | 0.72 | MAPT (0.49) | L3MBTL1POLBMAPT | |
| SCHEMBL9462045 | 0.71 | MAPT (0.45) | L3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650411-A | BACTERICIDES FOR HELICOBACTER DISEASES AND BACTERIA RESISTANCE | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-07-22 | — | — | US | disclosed |
| EP-0684821-A1 | SUBSTITUTED AZOLONE DERIVATIVES FOR TREATING DISEASES CAUSED BY HELICOBACTER | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018978-A1 | SUBSTITUTED AZOLONE DERIVATIVES FOR TREATING DISEASES CAUSED BY HELICOBACTER | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-09-01 | — | — | WO | disclosed |