Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | CYP8B1 | Q9UNU6 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815535 | 0.91 | DGAT1 (0.53) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9285138 | 0.89 | DGAT1 (0.57) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL8931704 | 0.89 | DGAT1 (0.57) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL8931684 | 0.87 | DGAT1 (0.60) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9285996 | 0.86 | DGAT1 (0.54) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL8931656 | 0.86 | DGAT1 (0.54) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9282291 | 0.86 | DGAT1 (0.62) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL8931733 | 0.86 | DGAT1 (0.62) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9279941 | 0.84 | DGAT1 (0.53) | DGAT1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9279947 | 0.84 | DGAT1 (0.53) | DGAT1MAPTCYP3A4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650411-A | BACTERICIDES FOR HELICOBACTER DISEASES AND BACTERIA RESISTANCE | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-07-22 | — | — | US | disclosed |