Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931841 | 0.85 | AGTR1 (0.50) | AGTR1PPARGAGTR2GSTM2 | |
| SCHEMBL8931806 | 0.85 | AGTR1 (0.50) | AGTR1PPARGAGTR2GSTM2 | |
| SCHEMBL8931891 | 0.85 | AGTR1 (0.50) | AGTR1PPARGAGTR2GSTM2 | |
| SCHEMBL8931896 | 0.83 | AGTR1 (0.49) | AGTR1PPARGAGTR2GSTM2 | |
| SCHEMBL8931878 | 0.81 | AGTR1 (0.50) | AGTR1PPARGAGTR2 | |
| SCHEMBL8931847 | 0.77 | AGTR1 (0.45) | AGTR1PPARGAGTR2 | |
| SCHEMBL23552634 | 0.73 | JAK2 (0.55) | — | |
| SCHEMBL8931824 | 0.69 | OPRK1 (0.51) | — | |
| SCHEMBL8931902 | 0.69 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8931809 | 0.69 | AGTR1 (0.48) | AGTR1PPARGAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |