Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 3/20 | 0.37 |
| ▸ | F3 | P13726 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931868 | 0.89 | PPARA (0.44) | PPARGPPARAPTPN11 | |
| SCHEMBL8931865 | 0.85 | PTPN11 (0.52) | MEN1KMT2APPARGKDM4EPTPN11 | |
| SCHEMBL7017402 | 0.78 | AGTR1 (0.44) | MAPTMEN1ALDH1A1HTTKMT2A | |
| SCHEMBL10696052 | 0.69 | RARB (0.59) | BIDMCL1KAT8BCL2L1BAK1 | |
| SCHEMBL8931862 | 0.66 | FFAR4 (0.47) | — | |
| SCHEMBL21073537 | 0.64 | KMT2A (0.39) | MAPTMEN1ALDH1A1HTTKMT2A | |
| SCHEMBL18840227 | 0.63 | CES2 (0.41) | KMT2APPARG | |
| SCHEMBL10395824 | 0.63 | CES2 (0.41) | KMT2APPARG | |
| SCHEMBL13390219 | 0.63 | CES2 (0.41) | KMT2APPARG | |
| SCHEMBL18116996 | 0.63 | CES2 (0.41) | KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |