Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932034 | 0.73 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8931831 | 0.68 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL8931812 | 0.67 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL8931794 | 0.65 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8931893 | 0.63 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8931821 | 0.62 | APEX1 (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL8931865 | 0.61 | PTPN11 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL8931823 | 0.61 | AGTR1 (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL8931804 | 0.61 | GABRA1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL6946448 | 0.59 | TSHR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |