Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931800 | 0.82 | EGLN3 (0.46) | HDAC1USP2MAPK1GABRA1GABRG2 | |
| SCHEMBL7016786 | 0.77 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7022829 | 0.74 | GABRA1 (0.46) | USP2MAPK1GABRA1GABRG2GABRB3 | |
| SCHEMBL8931804 | 0.71 | GABRA1 (0.42) | USP2MAPK1GABRA1GABRG2GABRB3 | |
| SCHEMBL8868152 | 0.68 | SMN1; SMN2 (0.50) | HDAC1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL13587963 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTKDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL10659395 | 0.66 | DGKA (0.55) | HDAC1USP2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8931820 | 0.66 | GABRA1 (0.45) | USP2MAPK1GABRA1GABRG2GABRB3 | |
| SCHEMBL8931989 | 0.65 | GABRA1 (0.48) | USP2MAPK1GABRA1GABRG2GABRB3 | |
| SCHEMBL11532390 | 0.65 | CA12 (0.58) | MAPK1SMN1; SMN2ALDH1A1HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |