Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912814 | 0.74 | GCGR (0.43) | SLC6A2GCGRAR | |
| SCHEMBL28248440 | 0.65 | CYP19A1 (0.46) | SLC6A2SLC6A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27668185 | 0.62 | SLC6A2 (0.61) | SLC6A2SLC6A4MC4RALDH1A1SMN1; SMN2 | |
| SCHEMBL5731601 | 0.62 | SLC6A2 (0.73) | SLC6A2SLC6A4 | |
| SCHEMBL28248935 | 0.62 | CYP19A1 (0.46) | SLC6A2SLC6A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2072429 | 0.61 | SLC6A4 (0.67) | SLC6A2SLC6A4 | |
| SCHEMBL2074103 | 0.61 | SLC6A4 (0.67) | SLC6A2SLC6A4 | |
| SCHEMBL6087730 | 0.61 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2073887 | 0.61 | SLC6A4 (0.67) | SLC6A2SLC6A4 | |
| SCHEMBL9195174 | 0.60 | SLC6A2 (1.00) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |