Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201233 | 0.82 | SLC6A2 (0.70) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL8845768 | 0.81 | SLC6A2 (0.68) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL8845698 | 0.81 | SLC6A2 (0.68) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL9194863 | 0.79 | SLC6A2 (0.65) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL9197969 | 0.79 | SLC6A2 (0.65) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL9194455 | 0.78 | SLC6A2 (0.63) | SLC6A2SLC6A4 | |
| SCHEMBL9199025 | 0.77 | SLC6A2 (0.62) | SLC6A2SLC6A4 | |
| SCHEMBL9198615 | 0.76 | SLC6A2 (0.59) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL9198601 | 0.76 | SLC6A2 (0.59) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL704340 | 0.75 | SLC6A2 (0.59) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471296-B1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0471296-A1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | claimed |
| EP-0471296-B1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0471296-A1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |