Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913033 | 0.75 | GRIN2B (0.42) | OXTRAVPR1AUSP30GRIN2B | |
| SCHEMBL7019918 | 0.66 | GAA (0.54) | TRPA1TSHRKDM4EALDH1A1GAA | |
| SCHEMBL7015221 | 0.64 | TRPA1 (0.57) | TRPA1TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL7020356 | 0.64 | MAPT (0.47) | TRPA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2770633 | 0.62 | CYP3A4 (0.58) | TRPA1ABL1USP30KDM4EALDH1A1 | |
| SCHEMBL3751793 | 0.62 | CYP3A4 (0.58) | TRPA1ABL1USP30KDM4EALDH1A1 | |
| SCHEMBL9025920 | 0.62 | FFAR1 (0.57) | OXTRAVPR1AFFAR1AKR1B1EGLN1 | |
| SCHEMBL7014174 | 0.62 | TRPA1 (0.53) | TRPA1TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL7014933 | 0.62 | TRPA1 (0.53) | TRPA1TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL7019183 | 0.61 | CYP1A2 (0.53) | TRPA1TSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |