Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 5/20 | 0.38 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932052 | 0.77 | TK1 (0.38) | TK1NT5MRNASE1 | |
| SCHEMBL8932071 | 0.77 | TOP2A (0.40) | TK1TOP2A | |
| SCHEMBL8931941 | 0.76 | TK1 (0.36) | TK1TOP2ANT5MRNASE1 | |
| SCHEMBL8597107 | 0.76 | TK1 (0.46) | TK1NT5MRNASE1 | |
| SCHEMBL6830442 | 0.75 | TK1 (0.42) | TK1NT5MRNASE1 | |
| SCHEMBL6830445 | 0.75 | TK1 (0.42) | TK1NT5MRNASE1 | |
| SCHEMBL8931997 | 0.75 | TK1 (0.35) | TK1 | |
| SCHEMBL25630176 | 0.74 | TK1 (0.41) | TK1NT5MRNASE1 | |
| SCHEMBL18315872 | 0.74 | TK1 (0.41) | TK1NT5MRNASE1 | |
| SCHEMBL8931965 | 0.72 | TOP2A (0.40) | TK1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |