Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932234 | 0.75 | KMT2A (0.49) | TGFBR1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL3631508 | 0.74 | CYP4F2 (0.34) | TGFBR1CYP4F2CYP4A11ATR | |
| SCHEMBL8932237 | 0.73 | — | — | |
| SCHEMBL8932284 | 0.72 | TGFBR1 (0.41) | TGFBR1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL29223502 | 0.72 | CYP4F2 (0.35) | TGFBR1CYP4F2CYP4A11ATR | |
| SCHEMBL8932235 | 0.71 | — | — | |
| SCHEMBL14726472 | 0.71 | CYP4F2 (0.42) | CYP4F2CYP4A11ATR | |
| SCHEMBL22604901 | 0.69 | GAA (0.42) | CYP4F2CYP4A11ATR | |
| SCHEMBL8932232 | 0.69 | CYP4F2 (0.44) | CYP4F2CYP4A11ATR | |
| SCHEMBL18758369 | 0.69 | CYP4F2 (0.37) | CYP4F2CYP4A11ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |