Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932234 | 0.84 | KMT2A (0.49) | TGFBR1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL6760672 | 0.77 | TGFBR1 (0.43) | TGFBR1PTGS2PTGS1L3MBTL1KMT2A | |
| SCHEMBL8932311 | 0.76 | KMT2A (0.46) | TGFBR1PTGS2PTGS1KMT2AALDH1A1 | |
| SCHEMBL8932244 | 0.76 | KMT2A (0.48) | TGFBR1PTGS2PTGS1KMT2ASCN9A | |
| SCHEMBL8932271 | 0.74 | KMT2A (0.39) | TGFBR1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL8932285 | 0.72 | TGFBR1 (0.34) | TGFBR1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL8932302 | 0.71 | KMT2A (0.44) | TGFBR1PTGS2PTGS1KMT2AALDH1A1 | |
| SCHEMBL8932318 | 0.69 | PKM (0.43) | HDAC1HDAC8HDAC6HDAC5PTGS2 | |
| SCHEMBL9004994 | 0.69 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5BLM | |
| SCHEMBL9005135 | 0.69 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | claimed |