Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506540 | 0.91 | IDO1 (0.44) | IDO1EPHX1LTA4HL3MBTL1APP | |
| SCHEMBL8932490 | 0.81 | EPHX1 (0.44) | IDO1EPHX1L3MBTL1APPALDH1A1 | |
| SCHEMBL8932525 | 0.79 | IDO1 (0.51) | IDO1EPHX1APPALDH1A1TP53 | |
| SCHEMBL6571608 | 0.76 | SLC6A4 (0.52) | IDO1EPHX1LTA4HL3MBTL1APP | |
| SCHEMBL8932405 | 0.74 | PPARG (0.52) | IDO1EPHX1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7088679 | 0.73 | SLC6A4 (0.58) | IDO1EPHX1L3MBTL1APPALDH1A1 | |
| SCHEMBL7881281 | 0.71 | SLC6A4 (0.52) | IDO1EPHX1APPALDH1A1TP53 | |
| SCHEMBL15314132 | 0.71 | SLC6A4 (0.56) | IDO1LTA4HL3MBTL1SMN1; SMN2SLC6A4 | |
| SCHEMBL769511 | 0.71 | IDO1 (0.59) | IDO1LTA4HAPPALDH1A1TP53 | |
| SCHEMBL62037 | 0.71 | IDO1 (0.59) | IDO1LTA4HAPPALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |