Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932455 | 0.75 | ALDH1A1 (0.37) | QRFPRALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8932505 | 0.73 | CHRM2 (0.36) | HTR7DRD1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11257616 | 0.67 | HTR7 (0.66) | HTR7DRD2DRD1DRD4DRD5 | |
| SCHEMBL28104559 | 0.66 | QRFPR (0.54) | QRFPRLMNA | |
| SCHEMBL30862623 | 0.64 | HTR7 (0.77) | HTR7DRD2DRD1DRD4DRD5 | |
| SCHEMBL2456684 | 0.64 | HTR7 (0.77) | HTR7DRD2DRD1DRD4DRD5 | |
| SCHEMBL2937482 | 0.61 | AOC3 (0.73) | HTR7AOC3CHRM2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8509376 | 0.60 | AOC3 (0.71) | HTR7ALDH1A1AOC3CHRM2SIGMAR1 | |
| SCHEMBL7618492 | 0.60 | ALDH1A1 (0.81) | HTR7DRD2DRD1DRD4DRD5 | |
| SCHEMBL8703033 | 0.59 | HRH1 (0.61) | HTR7DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |