Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932422 | 0.83 | CMA1 (0.45) | ALDH1A1LMNAMAPTHPGDHIF1A | |
| SCHEMBL8932430 | 0.83 | HSD17B10 (0.42) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9479861 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9414488 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL27362692 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7177077 | 0.74 | HTRA1 (0.44) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5412651 | 0.74 | DPP4 (0.41) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL19912952 | 0.74 | HTRA1 (0.44) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5405039 | 0.74 | HTRA1 (0.44) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8435103 | 0.74 | HTRA1 (0.44) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |