Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932507 | 0.83 | ALDH1A1 (0.39) | LMNAALDH1A1HPGDMAPTHIF1A | |
| SCHEMBL8932415 | 0.80 | ALDH1A1 (0.39) | KMT2AIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL8932639 | 0.79 | NAAA (0.41) | APPSIGMAR1IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL12992270 | 0.78 | SIGMAR1 (0.45) | APPSIGMAR1MAPT | |
| SCHEMBL9414462 | 0.78 | SIGMAR1 (0.45) | APPSIGMAR1MAPT | |
| Hydrochloric Acid SCHEMBL10506096 | 0.76 | IDO1 (0.40) | APPSIGMAR1TSHRKMT2AIDO1 | |
| SCHEMBL9414489 | 0.76 | SIGMAR1 (0.46) | APPSIGMAR1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8932546 | 0.75 | CRBN (0.44) | CMA1APPCRBNDAOLMNA | |
| SCHEMBL8308762 | 0.75 | IDO1 (0.44) | APPSIGMAR1TSHRKMT2AIDO1 | |
| SCHEMBL3518321 | 0.73 | CHRM1 (0.46) | APPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |