Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899955 | 0.75 | PTPN1 (0.66) | HPGDTTRMEN1KMT2AMAOA | |
| SCHEMBL8899950 | 0.75 | PTPN1 (0.66) | HPGDTTRMEN1KMT2AMAOA | |
| SCHEMBL10513710 | 0.70 | PIM1 (0.52) | PIM1PIM2PIM3GSK3BAKR1B1 | |
| SCHEMBL10513716 | 0.70 | PIM1 (0.52) | PIM1PIM2PIM3GSK3BAKR1B1 | |
| SCHEMBL8932676 | 0.70 | HPGD (0.40) | PIM1PIM2PIM3GSK3BAKR1B1 | |
| SCHEMBL8932678 | 0.70 | HPGD (0.40) | PIM1PIM2PIM3GSK3BAKR1B1 | |
| SCHEMBL10102393 | 0.69 | BRD4 (0.55) | — | |
| SCHEMBL623589 | 0.68 | PIM1 (0.59) | PIM1NAT1MEN1KMT2ARAB9A | |
| SCHEMBL624383 | 0.68 | SIRT1 (0.51) | PIM1GSK3BMEN1KMT2ARAB9A | |
| SCHEMBL624382 | 0.68 | SIRT1 (0.51) | PIM1GSK3BMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |