Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932678 | 1.00 | HPGD (0.40) | HPGDPIM1PIM2IGF1RGSK3B | |
| SCHEMBL8932729 | 0.72 | MAPT (0.38) | HPGDTDP1MAPTCISD1PTPN1 | |
| SCHEMBL8932677 | 0.70 | PIM1 (0.47) | HPGDPIM1PIM2IGF1RGSK3B | |
| SCHEMBL8899955 | 0.67 | PTPN1 (0.66) | HPGDKDM4EPOLBPTPN1 | |
| SCHEMBL8899950 | 0.67 | PTPN1 (0.66) | HPGDKDM4EPOLBPTPN1 | |
| SCHEMBL7515519 | 0.62 | IGF1R (0.44) | HPGDPIM1PIM2IGF1RGSK3B | |
| SCHEMBL7515515 | 0.62 | IGF1R (0.44) | HPGDPIM1PIM2IGF1RGSK3B | |
| SCHEMBL9838965 | 0.61 | GABRA1 (0.49) | HPGDKDM4EMAPT | |
| SCHEMBL5249763 | 0.61 | PTPN1 (0.52) | HPGDPIM1PIM2IGF1RGSK3B | |
| SCHEMBL12107430 | 0.60 | HPGD (1.00) | HPGDPIM1PIM2IGF1RGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |