Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 13/20 | 0.43 |
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932721 | 0.85 | PPARA (0.40) | KDRPPARGPPARAKDM4EPOLB | |
| SCHEMBL8932709 | 0.77 | KDR (0.40) | KDRPPARGPPARAKDM4EPOLB | |
| SCHEMBL6117631 | 0.73 | CA12 (0.54) | PPARGPPARAPPARD | |
| SCHEMBL18416801 | 0.70 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL7559600 | 0.68 | KDR (0.83) | KDRPPARGPPARAMAPT | |
| SCHEMBL4037331 | 0.68 | KDM4E (0.69) | KDRPPARGPPARAKDM4ELMNA | |
| SCHEMBL4031706 | 0.67 | KDR (0.57) | KDRPPARGPPARAKDM4EPPARD | |
| SCHEMBL6220972 | 0.67 | KDM4E (0.54) | PPARGPPARAKDM4ELMNAPPARD | |
| SCHEMBL6860260 | 0.67 | HTR6 (0.59) | PPARGPPARAPOLBPPARD | |
| SCHEMBL2928321 | 0.67 | PPARG (0.46) | PPARGPPARAKDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |