Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932710 | 0.77 | KDR (0.46) | KDRPPARGKDM4EPPARAMAPT | |
| SCHEMBL25811430 | 0.76 | PTGDR2 (0.51) | ACLYAGTR1PPARGPTGDRPTGDR2 | |
| SCHEMBL6117631 | 0.67 | CA12 (0.54) | ACLYPPARGPPARAPPARD | |
| SCHEMBL29839951 | 0.66 | AGTR1 (0.62) | ACLYAGTR1PTGDR2POLBPTGS2 | |
| SCHEMBL7192965 | 0.64 | AGTR1 (0.55) | AGTR1SRCLMNA | |
| SCHEMBL8687051 | 0.63 | SMN1; SMN2 (0.40) | KDRKDM4EMAPTPOLBLMNA | |
| SCHEMBL3562959 | 0.62 | AGTR1 (0.57) | ACLYAGTR1PPARGPTGDRPTGDR2 | |
| SCHEMBL29839883 | 0.62 | ACLY (0.64) | ACLYAGTR1PPARGPTGS2PPARD | |
| SCHEMBL2089931 | 0.62 | KDM4E (0.56) | KDM4EMAPTPOLBPTGS2 | |
| SCHEMBL12748656 | 0.62 | AKR1C3 (0.57) | PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |