Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP2 | P12104 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524329 | 0.78 | HTR2A (0.45) | HTR2AHTR2CROCK1FABP4CYP2A6 | |
| SCHEMBL16321366 | 0.78 | MCL1 (0.43) | HTR2AHTR2CSLC6A2ROCK1HTR7 | |
| SCHEMBL30235311 | 0.74 | PRKCI (0.59) | HTR2AHTR2CSLC6A2ROCK1HTR7 | |
| SCHEMBL856111 | 0.74 | PRKCI (0.59) | HTR2AHTR2CSLC6A2ROCK1HTR7 | |
| SCHEMBL17968774 | 0.73 | PDE2A (0.31) | PRKCI | |
| SCHEMBL8606795 | 0.72 | HDAC6 (0.57) | — | |
| SCHEMBL321199 | 0.71 | CDK4 (0.45) | HTR2AHTR2CSLC6A2HTR6PRKCI | |
| SCHEMBL29614841 | 0.71 | CDK4 (0.45) | HTR2AHTR2CSLC6A2HTR6PRKCI | |
| SCHEMBL4951865 | 0.71 | ACHE (0.40) | — | |
| SCHEMBL4951595 | 0.71 | PRKCI (0.37) | HTR2AHTR2CROCK1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |