1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL8932745

CC(Cl)(Cl)Cl.Clc1ccc(Cl)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
CYP2A6 P11509 1/20 0.61
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
SLC6A2 P23975 2/20 0.48
SLC6A3 Q01959 2/20 0.48
HTR2A P28223 1/20 0.48
SLC6A4 P31645 1/20 0.48
HRH1 P35367 1/20 0.48
HTR2B P41595 1/20 0.48
CHRNA4 P43681 1/20 0.48
TSHR P16473 5/20 0.48
MAPK1 P28482 3/20 0.48
HIF1A Q16665 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
IDO1 P14902 1/20 0.44
CYP19A1 P11511 3/20 0.42
ADRB2 P07550 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroethane SCHEMBL28366341 0.90 CYP1A2 (0.55) LMNACYP2A6MEN1KMT2ASLC6A2
SCHEMBL8322314 0.81 MEN1 (0.59) LMNACYP2A6MEN1KMT2ASLC6A2
SCHEMBL83653 0.81 MEN1 (0.59) LMNACYP2A6MEN1KMT2ASLC6A2
SCHEMBL677101 0.81 MEN1 (0.59) LMNACYP2A6MEN1KMT2ASLC6A2
Chlorophenothane SCHEMBL11570317 0.79 TSHR (0.86) LMNACYP2A6MEN1KMT2ASLC6A2
1,4-Dichlorobenzene SCHEMBL11243685 0.78
1,4-Dichlorobenzene SCHEMBL5191 0.78
1,3,5-Trichlorobenzene SCHEMBL23244766 0.77 TSHR (0.61) MEN1KMT2ATSHRMAPK1TDP1
SCHEMBL8743247 0.76 KMT2A (0.68) LMNACYP2A6MEN1KMT2ATSHR
SCHEMBL6552297 0.76 MEN1 (0.54) LMNACYP2A6MEN1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996024558-A1 METHOD AND APPARATUS FOR THERMAL DECOMPOSITION AND SEPARATION OF COMPONENTS WITHIN AN AQUEOUS STREAM HPR CORPORATION (US) 1996-08-15 WO disclosed