Trichloroethane

Trichloroethane

SCHEMBL28366341

CC(Cl)(Cl)Cl.Clc1ccc(-c2ccc(Cl)cc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
LMNA P02545 2/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 3/20 0.48
MAPK1 P28482 2/20 0.48
HIF1A Q16665 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
AHR P35869 1/20 0.48
ALOX5 P09917 1/20 0.44
KIF11 P52732 1/20 0.43
AKT1 P31749 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2A P28223 1/20 0.42
SLC6A4 P31645 1/20 0.42
HRH1 P35367 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL8932745 0.90 LMNA (0.61) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL3952742 0.83 CYP1A2 (0.73) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL11165087 0.83 CYP1A2 (0.73) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL28215 0.83 CYP1A2 (0.73) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL5049965 0.80 KIF11 (0.56) CYP1A2LMNATSHRMAPK1HIF1A
Methyl Alcohol SCHEMBL28374011 0.80 CYP1A2 (0.61) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL25437316 0.79 CYP1A2 (0.69) CYP1A2LMNACYP2A6TSHRMAPK1
Hydrogen Sulfide SCHEMBL10394839 0.79 CYP1A2 (0.69) CYP1A2LMNACYP2A6TSHRMAPK1
1,4-Dichlorobenzene SCHEMBL27654439 0.79 LMNA (0.80) CYP1A2LMNACYP2A6TSHRMAPK1
SCHEMBL17680283 0.78 MEN1 (0.52) CYP1A2LMNACYP2A6TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110711770-B Method for removing organochlorine compounds in soil through enhanced advanced oxidation and cooperative electrokinetic remediation of surface ion active agent 中国科学院南京土壤研究所 2021-10-01 CN claimed
CN-110695080-B Method for removing organochlorine compounds in soil through enhanced advanced oxidation and cooperative electrokinetic remediation of chelating agent 中国科学院南京土壤研究所 2021-05-04 CN claimed
CN-111250527-A Method for removing persistent organic pollutants in soil through Triton X-100 enhanced advanced oxidation in cooperation with electrokinetic remediation 中国科学院南京土壤研究所 2020-06-09 CN claimed
CN-110711770-A Method for removing organochlorine compounds in soil through enhanced advanced oxidation and cooperative electrokinetic remediation of surface ion active agent 中国科学院南京土壤研究所 2020-01-21 CN claimed
CN-110695080-A Method for removing organochlorine compounds in soil through enhanced advanced oxidation and cooperative electrokinetic remediation of chelating agent 中国科学院南京土壤研究所 2020-01-17 CN claimed
CN-111707768-B Method for detecting 22 organochlorine pesticide residues in total glucosides of paeony bulk drug 宁波立华制药有限公司 2023-03-17 CN disclosed
CN-113671068-B Method for analyzing environmental pollutant targeted exposure group in blood plasma and application thereof 暨南大学 2023-01-24 CN disclosed
CN-113671068-A Method for analyzing environmental pollutant targeting exposure component in blood plasma and application thereof 暨南大学 2021-11-19 CN disclosed
CN-111707768-A Method for detecting 22 organochlorine pesticide residues in total glucosides of paeony bulk drug by gas chromatography-mass spectrometry 宁波立华制药有限公司 2020-09-25 CN disclosed