Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449561 | 0.73 | L3MBTL1 (0.40) | ALDH1A1POLBKMT2ALMNAGAA | |
| SCHEMBL10584998 | 0.73 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL22660135 | 0.71 | L3MBTL1 (0.52) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL8530708 | 0.70 | ALDH1A1 (0.37) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL4753838 | 0.70 | CA12 (0.47) | ALDH1A1GAASTAT3 | |
| SCHEMBL1995195 | 0.70 | GAA (0.54) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL17941037 | 0.70 | L3MBTL1 (0.48) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL8056281 | 0.70 | GAA (0.42) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL4754272 | 0.70 | GAA (0.42) | ALDH1A1POLBKMT2ALMNAGAA | |
| SCHEMBL4757045 | 0.69 | GAA (0.45) | ALDH1A1KMT2ALMNAGAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | disclosed |