Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.82 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823916 | 1.00 | HRH3 (0.82) | HRH3ACHERAD52 | |
| SCHEMBL2824040 | 0.93 | HRH3 (0.83) | HRH3ACHERAD52 | |
| SCHEMBL2819923 | 0.91 | HRH3 (0.81) | HRH3ACHERAD52 | |
| SCHEMBL8933102 | 0.91 | LTA4H (0.72) | HRH3 | |
| SCHEMBL12061373 | 0.89 | HRH3 (0.90) | HRH3ACHERAD52 | |
| SCHEMBL2819860 | 0.88 | HRH3 (0.77) | HRH3ACHERAD52 | |
| SCHEMBL3581930 | 0.85 | HRH3 (0.89) | HRH3ACHERAD52 | |
| SCHEMBL23291161 | 0.85 | HRH3 (0.82) | HRH3ACHERAD52 | |
| SCHEMBL2821210 | 0.85 | HRH3 (0.85) | HRH3ACHERAD52 | |
| SCHEMBL491770 | 0.85 | HRH3 (0.82) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |