Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.72 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.69 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.69 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932975 | 0.91 | HRH3 (0.82) | HRH3 | |
| SCHEMBL2823916 | 0.91 | HRH3 (0.82) | HRH3 | |
| SCHEMBL7134882 | 0.84 | LTA4H (1.00) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL15876475 | 0.84 | LTA4H (0.72) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL9056254 | 0.84 | HRH3 (0.83) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL10896960 | 0.84 | LTA4H (0.72) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL2824040 | 0.83 | HRH3 (0.83) | HRH3 | |
| SCHEMBL23291141 | 0.83 | PSMB1 (0.71) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL6655030 | 0.83 | HRH3 (0.74) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL15876462 | 0.83 | PSMB1 (0.71) | LTA4HPSMB1PSMB5PSMB2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |