Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674277 | 0.82 | BLM (0.59) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL6725266 | 0.82 | BLM (0.59) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL27973999 | 0.74 | BLM (0.53) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL11596247 | 0.71 | BLM (0.67) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL5004593 | 0.71 | BLM (0.67) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL28136645 | 0.71 | BLM (0.46) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL20299947 | 0.70 | BLM (0.51) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL13809480 | 0.70 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL25583339 | 0.69 | BLM (0.59) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL9137764 | 0.69 | FDPS (0.50) | MEN1KMT2ATSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023813-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO SH2 DOMAINS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-08-08 | — | — | WO | disclosed |