Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | RARG | P13631 | 6/20 | 0.44 |
| ▸ | RARA | P10276 | 5/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370340 | 0.78 | KDM4E (0.56) | KDM4ERARBRARGRARAGABRB1 | |
| SCHEMBL29912865 | 0.78 | KDM4E (0.56) | KDM4ERARBRARGRARAGABRB1 | |
| SCHEMBL19774287 | 0.76 | KDM4E (0.50) | KDM4ERARBRARGRARAGRIN2D | |
| SCHEMBL10722538 | 0.76 | SLC6A2 (0.43) | GABRB1GABRB2KMT2ACYP1A2TSHR | |
| SCHEMBL8081677 | 0.74 | KDM4E (0.55) | KDM4ERARBRARGRARAGRIN2D | |
| SCHEMBL28852413 | 0.74 | KDM4E (0.51) | KDM4ERARBRARGRARAGABRB1 | |
| SCHEMBL11460818 | 0.73 | KDM4E (0.54) | KDM4ERARBRARGRARALMNA | |
| SCHEMBL632517 | 0.72 | KMT2A (0.38) | KDM4ELMNAKMT2A | |
| SCHEMBL17965782 | 0.72 | SRC (0.50) | LMNAKMT2ATDP1TSHR | |
| SCHEMBL7907125 | 0.72 | RARB (0.54) | KDM4ERARBRARGRARAGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023813-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO SH2 DOMAINS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-08-08 | — | — | WO | disclosed |