Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARG | P13631 | 4/20 | 0.49 |
| ▸ | RARA | P10276 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29912865 | 1.00 | KDM4E (0.56) | KDM4ERARBRARGRARAGABRA1 | |
| SCHEMBL28852413 | 0.95 | KDM4E (0.51) | KDM4ERARBRARGRARAGABRA1 | |
| SCHEMBL8390404 | 0.93 | GABRA1 (0.50) | KDM4ERARBRARGRARAGABRA1 | |
| SCHEMBL1415273 | 0.86 | CES2 (0.55) | KDM4EGABRA1GABRG2GABRB3GABRA3 | |
| Terephthalic Acid SCHEMBL11412636 | 0.84 | SLC7A5 (0.54) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL23458554 | 0.84 | KMT2A (0.49) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL539749 | 0.84 | CES2 (0.48) | KDM4EGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL25736545 | 0.84 | GABRA1 (0.44) | KDM4EGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL40750 | 0.84 | SLC7A5 (0.56) | KDM4ESLC7A5CA1CA2CA12 | |
| SCHEMBL30163785 | 0.84 | SLC7A5 (0.56) | KDM4ESLC7A5CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11029528-A | — | — | None | — | — | JP | disclosed |
| US-20050043304-A1 | Novel amine derivative having human beta-tryptase inhibitory activity and drugs containing the same | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1445250-A1 | NOVEL AMINE DERIVATIVE HAVING HUMAN BETA-TRYPTASE INHIBITORY ACTIVITY AND DRUGS CONTAINING THE SAME | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
| JP-H1129528-A | PRODUCTION OF T-BUTYL ESTERS OF HYDRO-AROMATIC CARBOXYLIC ACID | HONSHU CHEM IND CO LTD | 1999-02-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043304-A1 | Novel amine derivative having human beta-tryptase inhibitory activity and drugs containing the same | TPSAB1, TPSB2, TPSD1 | KDM4E 1687/4885RARB 3997/4885RARG 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.