SCHEMBL893309

SCHEMBL893309

CC1(C)CC(C2(OC(=O)CC(=O)O)CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
EZH2 Q15910 3/20 0.32
TSHR P16473 1/20 0.32
POLB P06746 3/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30
USP2 O75604 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2574870 0.87 GAA (0.33) GAA
SCHEMBL2688832 0.83 GPR84 (0.35) KMT2ATSHRMEN1MAPTHSD17B10
SCHEMBL4780506 0.74 GAA (0.31) GAA
SCHEMBL11354021 0.72 GAA (0.51) GAAHTTKMT2AKDM4EEZH2
SCHEMBL28472859 0.66 HTT (0.39) GAAHTTKMT2AKDM4EEZH2
SCHEMBL563911 0.63 GAA (0.51) GAAHTTKMT2AKDM4EEZH2
SCHEMBL26939247 0.62 CYP2C19 (0.34) KMT2ATSHRMEN1HSD17B10
SCHEMBL11547009 0.62 ALOX15 (0.38) GAAHTTKMT2AKDM4EEZH2
SCHEMBL4016063 0.62 CYP1A2 (0.42) GAAHTTKMT2AKDM4ETSHR
SCHEMBL27849687 0.61 GAA (0.47) GAAHTTKMT2AKDM4EEZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS AAAS, H1-5, H1-2 GAA 874/4885HTT 449/4885KMT2A 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.