Hexane

Hexane

SCHEMBL8933295

CC(C)O.CCCCCC.CCOP(=O)(O)O

nearest known ligand 0.57

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.57
LPAR1 Q92633 5/20 0.57
LPAR2 Q9HBW0 3/20 0.57
LPAR5 Q9H1C0 2/20 0.51
LPAR6 P43657 1/20 0.47
LPAR4 Q99677 1/20 0.47
ENPP2 Q13822 1/20 0.47
SMPD1 P17405 3/20 0.47
SGPL1 O95470 4/20 0.45
S1PR4 O95977 2/20 0.44
S1PR1 P21453 2/20 0.44
S1PR3 Q99500 2/20 0.44
S1PR5 Q9H228 2/20 0.44
S1PR2 O95136 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSPO P30536 1/20 0.44
TMEM97 Q5BJF2 1/20 0.44
SIGMAR1 Q99720 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL10371616 0.91 LPAR3 (0.67) LPAR3LPAR1LPAR2LPAR5SMPD1
Heptane SCHEMBL5657 0.89 LPAR3 (0.71) LPAR3LPAR1LPAR2LPAR5LPAR6
Butane SCHEMBL2850741 0.81 LPAR3 (0.52) LPAR3LPAR1LPAR2LPAR5
Tetrabuthylammonium SCHEMBL26929178 0.81 LPAR3 (0.55) LPAR3LPAR1LPAR2LPAR5SMPD1
SCHEMBL40792 0.81
SCHEMBL27666183 0.81 TSHR (0.56) LPAR3LPAR1LPAR2
Propylene Glycol SCHEMBL28768835 0.80 TDP1 (0.46) LPAR3LPAR1LPAR2LPAR5
Hexane SCHEMBL2774153 0.79 FDPS (0.52) LPAR3LPAR1LPAR2SMPD1
SCHEMBL2471601 0.78 PPARD (0.39) LPAR3LPAR1LPAR2LPAR5
SCHEMBL2470581 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996022770-A1 ANTI-INFLAMMATORY COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-01 WO disclosed