Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.71 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.71 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.71 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.52 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.47 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL10371616 | 0.97 | LPAR3 (0.67) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| Hexane SCHEMBL8933295 | 0.89 | LPAR3 (0.57) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL29194856 | 0.88 | S1PR2 (0.61) | LPAR3LPAR1LPAR2LPAR5 | |
| Butane SCHEMBL2850741 | 0.87 | LPAR3 (0.52) | LPAR3LPAR1LPAR2LPAR5 | |
| Tetrabuthylammonium SCHEMBL26929178 | 0.87 | LPAR3 (0.55) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL27666183 | 0.87 | TSHR (0.56) | LPAR3LPAR1LPAR2 | |
| SCHEMBL40792 | 0.87 | — | — | |
| SCHEMBL30489750 | 0.86 | DNM1 (0.56) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| Undecanoate SCHEMBL504259 | 0.86 | GPR84 (0.63) | LPAR3LPAR1LPAR2 | |
| Nonanoate SCHEMBL503669 | 0.86 | GPR84 (0.63) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |