Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | PRKCA | P17252 | 4/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributyrin SCHEMBL601928 | 0.98 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL23825 | 0.98 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL31235642 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL29693663 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL28197890 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL28349511 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL19300633 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL8206257 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL21289215 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL30241899 | 0.96 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569680-A | ADMINISTERING TO INHIBIT THE PRODUCTION OF INTERLEUKIN-8 IN INTESTINAL EPITHELIAL CELLS | TRUSTEES OF THE UNIV. OF PENNA | 1996-10-29 | — | — | US | disclosed |
| WO-1996025380-A1 | THE USE OF TRIBUTYRIN IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-08-22 | — | — | WO | disclosed |