Tributyrin

Tributyrin

SCHEMBL601928

CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC.CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.72
LMNA P02545 1/20 0.72
PRKCA P17252 4/20 0.61
PRKCE Q02156 2/20 0.61
PRKCQ Q04759 2/20 0.61
PRKCD Q05655 2/20 0.61
LPAR3 Q9UBY5 7/20 0.57
LPAR1 Q92633 4/20 0.57
ENPP2 Q13822 3/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LPAR2 Q9HBW0 2/20 0.55
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tributyrin SCHEMBL23825 1.00 ALDH1A1 (0.72) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL31235642 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL29693663 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL28197890 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL28349511 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL8206257 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL19300633 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL8933438 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21289215 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
Tributyrin SCHEMBL30241899 0.98 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
WO-2021045554-A1 PHARMACEUTICAL COMPOSITION COMPRISING PROCESSED FISH PRODUCT AND/OR PROCESSED SOYBEAN PRODUCT AS ACTIVE INGREDIENT 장영진 2021-03-11 WO disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
CN-105828809-A Microcapsules With Polymeric Coating Comprising A Lipid And An Active Agent 费森尤斯卡比德国有限公司 2016-08-03 CN disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
US-8288136-B2 Production of peracids using an enzyme having perhydrolysis activity E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
CN-102366413-A Application of glyceryl tributyrate in preparation of drug for treating cardiovascular disease UNIV SHANGHAI JIAOTONG 2012-03-07 CN disclosed
CN-102365320-A Plastisols containing glycerol esters as plasticizers GENOVIQUE SPECIALTIES HOLDINGS 2012-02-29 CN disclosed
US-8114908-B2 Production of peracids using an enzyme having perhydrolysis activity E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-14 US disclosed
US-20110244535-A1 Production Of Peracids Using An Enzyme Having Perhydrolysis Activity DUPONT US HOLDING, LLC 2011-10-06 US disclosed
US-20100168237-A1 PRODUCTION OF PERACIDS USING AN ENZYME HAVING PERHYDROLYSIS ACTIVITY DUPONT US HOLDING, LLC 2010-07-01 US disclosed
US-20090312420-A1 Production Of Peracids Using An Enzyme Having Perhydrolysis Activity DUPONT US HOLDING, LLC 2009-12-17 US disclosed
EP-0600038-A4 PROCESS FOR ALKOXYLATION OF ESTERS AND PRODUCTS PRODUCED THEREFROM. VISTA CHEMICAL (US) 1995-05-17 EP disclosed
EP-0600038-A1 PROCESS FOR ALKOXYLATION OF ESTERS AND PRODUCTS PRODUCED THEREFROM. VISTA CHEMICAL (US) 1994-06-08 EP disclosed
WO-1993004030-A1 PROCESS FOR ALKOXYLATION OF ESTERS AND PRODUCTS PRODUCED THEREFROM VISTA CHEMICAL COMPANY (US) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168237-A1 PRODUCTION OF PERACIDS USING AN ENZYME HAVING PERHYDROLYSIS ACTIVITY CES2, CA7, HAO2 ALDH1A1 217/4885LMNA 4385/4885PRKCA 1511/4885
US-20090312420-A1 Production Of Peracids Using An Enzyme Having Perhydrolysis Activity CES2, CA7, HAO2 ALDH1A1 217/4885LMNA 4385/4885PRKCA 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.