Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310869 | 0.77 | TSHR (0.35) | TSHRSMN1; SMN2GAAMAPK1HPGD | |
| SCHEMBL10470932 | 0.77 | CHRM1 (0.51) | LMNASMN1; SMN2MAPTGABRA1GABRG2 | |
| SCHEMBL7306590 | 0.77 | PDE4D (0.61) | TSHRLMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL10471753 | 0.75 | MAPT (0.38) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10470314 | 0.75 | HTT (0.40) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10471515 | 0.75 | GABRA1 (0.52) | TSHRMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL7370183 | 0.75 | OPRK1 (0.54) | LMNAGAAGABRA1GABRG2GABRB3 | |
| SCHEMBL10471793 | 0.74 | CHRM1 (0.54) | LMNAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11655306 | 0.74 | PDE4A (0.49) | SMN1; SMN2MAPTL3MBTL1MAPK1PDE4D | |
| Hydrochloric Acid SCHEMBL11654812 | 0.74 | OPRK1 (0.53) | LMNAGAAGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |