Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468522 | 0.85 | KMT2A (0.53) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL639945 | 0.83 | POLB (0.46) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL7475532 | 0.83 | CA1 (0.48) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL6788195 | 0.79 | POLB (0.48) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL13656103 | 0.78 | POLB (0.49) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL13170107 | 0.78 | POLB (0.49) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL15695551 | 0.78 | PTGS1 (0.51) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL23182201 | 0.77 | POLB (0.47) | POLBHTTNPSR1L3MBTL1CA1 | |
| SCHEMBL9278678 | 0.76 | ESR1 (0.43) | NPSR1CA1CA2CA7CA9 | |
| SCHEMBL3812849 | 0.75 | CA1 (0.52) | POLBHTTNPSR1L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |