Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933613 | 0.85 | POLB (0.47) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL639945 | 0.83 | POLB (0.46) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL7475532 | 0.83 | CA1 (0.48) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL20299495 | 0.81 | HTT (0.42) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL4628923 | 0.80 | KMT2A (0.56) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL11383904 | 0.79 | KMT2A (0.48) | KMT2AL3MBTL1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL6788195 | 0.79 | POLB (0.48) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL8473051 | 0.78 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL7885098 | 0.78 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL6400516 | 0.78 | KMT2A (0.55) | KMT2APOLBHTTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428432-B2 | Thienopyrimidine derivatives having stereo configurations and use thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-09-30 | — | — | US | disclosed |
| CN-113924303-B | Thienopyrimidine derivatives with steric configuration and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-3571205-B1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| CN-115160340-A | Small molecule compound with ACK1 inhibitory activity and application thereof | 四川大学华西医院 | 2022-10-11 | — | — | CN | disclosed |
| US-20220267346-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-3995498-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-05-11 | — | — | EP | disclosed |
| EP-3995498-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-05-11 | — | — | EP | disclosed |
| CN-113924303-A | Thienopyrimidine derivatives with spatial configuration and application thereof in medicines | 广东东阳光药业有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108341830-B | Thienopyrimidine derivatives and their use in medicine | 广东东阳光药业有限公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2021000242-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-01-07 | — | — | WO | disclosed |
| WO-2021000242-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-01-07 | — | — | WO | disclosed |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-11-21 | — | — | US | disclosed |
| CN-108341830-A | Thienopyrimidine derivative and its application in drug | 广东东阳光药业有限公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| CN-1292697-A | Anti-viral compound | LILLY CO ELI (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1991011999-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267346-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | ACACA, ACACB, ACAT2 | KMT2A 2955/4885POLB 1091/4885HTT 2730/4885 |
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | ACACA, ACACB, PC | KMT2A 2582/4885POLB 1001/4885HTT 2214/4885 |
| US-12428432-B2 | Thienopyrimidine derivatives having stereo configurations and use thereof in medicine | ACACA, ACACB, ACAT2 | KMT2A 2955/4885POLB 1091/4885HTT 2730/4885 |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | ACACA, ACACB, PC | KMT2A 2582/4885POLB 1001/4885HTT 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.