Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933458 | 0.97 | FPR2 (0.32) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933714 | 0.95 | FPR2 (0.35) | PDE4AFASNFPR2KDM1ACYP3A4 | |
| SCHEMBL8932672 | 0.93 | KDM1A (0.37) | FASNFPR2KDM1ACYP3A4CYP2C9 | |
| SCHEMBL8933682 | 0.90 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933706 | 0.89 | FPR2 (0.35) | FASNFPR2KDM1ACYP3A4CYP2C9 | |
| SCHEMBL8959335 | 0.88 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933435 | 0.88 | FPR2 (0.33) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933299 | 0.87 | CNR2 (0.37) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933654 | 0.87 | RARB (0.34) | PDE4APDE4BPDE4CPDE4DFASN | |
| SCHEMBL8933708 | 0.87 | RARB (0.34) | PDE4APDE4BPDE4CPDE4DFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |